15 results
diagnosis lupus sle druginduced erythematosus hemophagocytic hlh lymphohistiocytosis oncology summary systemic activation antibody antinxp2 antinxp2dm aplastic arteritis autoimmune cerebritis classification
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... Treatment: ... result from low blood ... #oncology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... Treat primary cause ... #treatment #management ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic complaints- anemia ... (Cornelia NEJM ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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