13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... (Hemolysis, Elevated ... child * Severe cases ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... (Hemolysis, Elevated ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • Pregnancy: HELLP ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... diagnosis #icp #HELLP
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... biliary obstruction, HELLP ... Syndrome, Celiac ... Causes #Acute #algorithm ... #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Differential #Diagnosis #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
to synthesis - rises ... Bilirubin: RBC (hemolysis ... • Gilbert's syndrome ... • Hemolysis ... #differential #Hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... hyperbilirubinemia syndrome ... without evidence of hemolysis ... or liver injury ... Congenital #bilirubin #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... at that stage rather ... presence of metabolic syndrome ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver