11 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... Dermatomyositis ... can present with rash ... including heliotrope rash ... Myositis #diagnosis #rheumatology
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... 1) heliotrope rash ... usually indicates myopathy ... Gottrons #Papules #Clinical ... #Photo
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash ... : • Symptoms limited
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
with heliotrope rash ... 1) heliotrope rash ... usually indicates myopathy ... #dermatology #clinical ... #photo
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
poikiloderma in Dermatomyositis ... other signs and symptoms ... #Rash #Dermatomyositis ... #Dermatology #Clinical ... #Photo #Neck
Poikiloderma of Civatte (Photodamage Poikiloderma)

Poikiloderma in general is a common finding in older individuals with chronic
poikiloderma of dermatomyositis ... other signs and symptoms ... #Photodamage #Rash ... #Dermatology #Clinical ... #Photo #Neck
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... #DIL #rheumatology