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diagnosis clinical differential management hematology erythematosus systemic skinrash table myositis sign skin syphilis thrombocytopenia aflp algorithm autoimmune blood druginduced gottrons
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #sle #comparison
Heliotrope Rash in Dermatomyositis Peri-orbital edema and the heliotrope rash that we are all familiar with. Eyelid
Heliotrope Rash ... the heliotrope rash ... The heliotrope rash ... #Heliotrope #Rash ... #Photo #Face
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Management #Summary #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-phospholipid) M Malar Rash ... D Discoid Rash ... Antinuclear Antibody (ANA ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... annular rash on ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Women • ~20% of cases ... Men • ~50% of cases ... Women • ~30% of cases
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... caused by other ... Diagnosis #Clinical #Photo ... #Dermatology
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