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Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Diagnosis #Algorithm #Causes
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... == Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... turnover • Acute blood
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... ischemia-induced RBC ... hemolysis) • RBC ... Diagnosis #Algorithm #causes
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... Hematuria: 3 or more RBC ... hematuria: - RBC ... - Dysmorphic RBC ... #renal #urine #blood
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... parasitemia - normocytic RBCs ... multiples per RBC ... P. falciparum causes ... human malaria cases
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Fe/TlBC, MCV/RBC ... Deficiency (Eg Causes ... : Chronic Blood ... inclusions in RBC
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Diagnosis #Algorithm #Causes
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Urinalysis >3 RBCs ... casts, dysmorphic ... RBCs)? ... Nephrology if cause ... Workup #urology #blood
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... 2) LOOK FOR a cause
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Volume Reduced RBC ... • Washed RBC ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
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