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Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Relative - Normal RBC ... Idiopathic JAK-2 Positive ... determination, Smoking, positive ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
- Monomorphic RBCs ... - Dysmorphic RBCs ... Granular Casts - WBC ... Cast - RBC Cast
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Presentation (Pulmonary ... : - ANCA-positive ... Investigations • Labs: CBC ... proteinuria, dysmorphic RBCs
Urinalysis Interpretation (UA) Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial cells, pH #Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
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 The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... WBC and platelets ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
glomerular hematuria (RBC ... or dysmorphic RBCs
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... autoantibodies: positive ... → schizocytes, Positive
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Glomerular Proteinuria (Positive ... urine sediment - WBC ... /RBC casts
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