31 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... Intake (diet) - Activation ... Hypocalcemia #Diagnosis #Management ... endocrinology #differential ... #algorithm
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
blood vessels, leading ... oxide release - Activation ... Medication #Causes #Differential ... #Pharmacology #Pathophysiology
Pathophysiology of Hepatorenal Syndrome - Dilation of splanchnic arteries initially compensated by increased CO eventually decompensates
Pathophysiology ... decompensates with activation ... RAAS, SNS, ADH) leading
In July 2015 the ACC/AHA proposed and published an algorithm to help stratify cardiac arrest patients
and published an algorithm ... emergent cath lab activation ... CardiacArrest #Algorithm ... CathLab #NSTEMI #Activation ... Stratfication #Management
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
gets activated leading ... skin, and brain leading ... by endothelial activation ... lysoganglioside leading ... Rheumatic #Fever #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
triggering their activation ... enhance B cell activation ... see Complement Activation ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Diagnosis Algorithm ... tourniquet while drawing ... #Diagnosis #Algorithm ... potassium #high #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... IFN-y) → Excessive activation ... Lymphohistiocytosis #diagnosis #management