24 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders #Classification ... #differential #algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... , Hb), Hepatic dysfunction ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... this group as well ... components of the algorithm ... #Diagnosis #Management ... Infant #StepByStep #Algorithm
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Emergency Management ... ECG and rate of rise ... Shift K+ into cells ... prevent further rise ... #algorithm #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Attempt if high risk ... severe APLS, organ dysfuxtion ... APML #diagnosis #management
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
IDSA Algorithm for ... the Management ... 12 000 or <400 cells ... oral antibiotic treatment ... evidence of organ dysfunction
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
anaerobe, SIow growing ... carbon loving' Risk ... of PCR is not well ... infectiousdiseases #diagnosis #management ... #treatment
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
cytokines, complement activation ... death), T-cell ... COMMON CAUSES + RISK ... • Risk factors ... INITIAL MANAGEMENT
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... is absent the risk ... of reactivation ... #Treatment #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... Low or absent NK cell ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management