23 results
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... - Defects in RBC ... - Defects in RBC ... environment #Pathophysiology ... Hemolytic #Anemia #hematology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... shape, HbS induces RBC ... This leads to RBC ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... Anemia #diagnosis #management ... #treatment #rheumatology
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Contents #Volume #Hematology ... #Management #Table
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... #Irradiation #RBC ... #Indications #Hematology ... #BloodBank #Management
JAK Inhibitors in 2019

Role in the therapeutic strategy in 2019
 • RA: 2nd line after failure
strategy in 2019 • RA ... #Indications #Rheumatology ... #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... hydration • RBC ... causes #treatment #management ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... Management: • ... diagnosis and management ... #Treatment #Hematology