33 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... , necrosis and pain ... #Pathophysiology ... Complications #Hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... infection • Lyme disease ... gangrenosum • IBD • RA ... dermatology #joint #pain ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... IBD, Whipple's disease ... Vasculitis (e.g., PAN ... conditions #joint #pain ... differential #diagnosis #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... categories of joint disease ... rheumatoid arthritis (RA ... necrosis, and Paget disease ... #MSK #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... Symmetrical: • RA ... Differential #Diagnosis #MSK ... #rheumatology #
Shoulder Impingement Syndrome (SIS): Signs and Symptoms

Repetitive Overhead Activity, Scapular Dyskinesis -> Scapulohumeral mechanics become altered
rotator cuff (RC ... test - Pain at ... reproduces the pain ... signs #symptoms #msk ... #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
Clinical findings • Pain ... more constant as disease ... progresses) - X-ray ... thoracic kyphosis, X-ray ... AnkylosingSpondylitis #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
-> Sudden eye pain ... Pericarditis) -> Chest Pain ... pleuritic chest pain ... interstitial lung disease ... #pathophysiology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... Rheumatoid Arthritis (RA ... Differential #Diagnosis #rheumatology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
on axillary x-ray ... capsule or bone -> Pain ... signs #symptoms #msk ... #orthopedics #pathophysiology