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differential algorithm management causes clinical cardiology radiology pulmonary pocus table signs comparison symptoms neurology classification hematology pathophysiology peds nephrology workup
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... Reticulocytes, smear ... MAHA likely: • Smear ... : schistocytes > ... #Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... blue arrow) - schistocytes ... arrow) Peripheral smear ... Hematology #Pathology #Smear
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia 1) DIAGNOSE ... C3d • Blood smear ... Differential → schizocytes ... Hemolytic #Anemia #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Peripheral blood smear ... transfusions) • Schistocytes ... #Differential #Diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
reactant Blood smear ... • Expected: Schistocytes ... ISTH #Scoring #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Peripheral smear ... : Schistocytes, ... studies - PBS: + Schistocytes ... #Coagulation #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... Peripheral blood smear ... - Shows schistocytes ... ThromboticThrombocytopenicPurpura #Diagnosis
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
TTP) Look for schistocytes ... on peripheral smear ... Uremic #Syndrome #diagnosis
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
Schistocytes - The ... Also called schizocytes ... Schistocytes are ... Schistocytes are ... BloodSmear #Blood #Smear
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia Schistocytes ... Peripheral #Blood #Smear
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