9 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... Trousseau's • Malignant hypertension ... anemia" • HELLP ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... anemia • ... MAHA (TTP, DIC, HUS ... Extravascular #Differential ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... DIC, TTP, HELLP, HUS ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED ... Failure 1 H Hypertension ... Bleeding history/anemia ... #HASBLED #Comparison ... AFib #Diagnosis #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Valves, AS - HTN ... #Differential # ... Diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... : • DIC, TTP/HUS ... #Diagnosis #hematology ... #nonpalpable #dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Viral Infection Clinical ... younger pts) Differential ... #anemia #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Cell population has ... bacteremia and hypotension ... #differential # ... neutrophil #WBC #CBC #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology