10 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... in Systemic Lupus ... #diseases #SLE ... Erythematosus #venn #nephrology ... #nephritis #classification
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... or 0.5 g/day → renal ... by 12 months Classification ... #rheumatology #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... failure • Chronic ... • Interstitial nephritis ... • Drugs • Diabetic ... Diagnosis #algorithm #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
losses, Diuretic ... : • Acute or chronic ... Hypervolemia, UNa ... < 20 • Nephrotic ... Algorithm #Causes #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... (nephrotic-range ... APLA/LAC: • Renal ... : • Chronic B-cell
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
trauma - Ischemic colonic ... (Uncontrolled diabetes ... deficiency • Renal ... insufficiency/Failure • SLE ... potassium #high #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... kidney disease, and nephrotic ... Hyponatremia • Hypercalcemia ... kidney disease, and nephrotic ... Excretion #Diuresis #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
trauma - Ischemic colonic ... (Uncontrolled diabetes ... deficiency • Renal ... insufficiency/Failure • SLE ... potassium #high #nephrology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... heart failure • Diabetes ... discoloration) • Chronic ... renal failure ... discoloration) • Nephrotic
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
diseases: syßtemic lupus ... erythematosus (SLE ... Diabetes, diabetic ... Chronic kidney disease ... High #Potassium #Classification