25 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Induction Rx: high-dose ... Erythematosus #SLE ... #CNS #neurology ... cerebritis #diagnosis #management
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... differential #diagnosis #management ... #nephrology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Bullous systemic lupus ... tarda • Diabetic ... Vesiculobullous #SkinRash ... #dermatology #Differential
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... • Specific for SLE ... Severe disease- high ... #Systemic #Lupus ... #rheumatology #management
Necrotizing Fasciitis: Note the extensive edema, erythema, bullae formation, and necrosis in this patient's thigh. At
this patient's thigh ... presentation, this diabetic ... Clinical #Photo #Dermatology ... #SkinRash #Necrotizing
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... treat non-renal SLE ... treat extra-renal SLE ... Algorithm #Treatment #management ... #nephrology
Subacute Cutaneous Lupus erythematosus (SCLE): Erythematous, warm, plaques in light exposed distribution (also on patient's neck),
Subacute Cutaneous Lupus ... Subacute Cutaneous Lupus ... Images #Clinical #Dermatology ... #SkinRash #Subaute ... #Cutaneous #Lupus
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... in 10 to 40% of SLE ... BaillouChloe #Lupus ... #rheumatology #nephrology
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Proliferative Lupus ... Agent plus mod-high ... Proliferative #Lupus ... #Nephritis #management ... #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Sodium >145 mmol/L High ... Osmotic diuresis (see ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology