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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
#Nephritis #SLE ... Classification #Classes ... #differential # ... diagnosis #management ... #nephrology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Bullous systemic lupus ... tarda • Diabetic ... Vesiculobullous #SkinRash #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... treat non-renal SLE ... treat extra-renal SLE ... Algorithm #Treatment #management ... #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... #CNS #neurology ... cerebritis #diagnosis #management
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... acidosis (type 1 of 2) ... Ureterosigmoidostomy, Diabetic ... #hypokalemia #differential ... #nephrology #potassium
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential ... (MPA) • SLE ... • HTN • Diabetes ... #Proteinuria #Nephrology ... #Differential #
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... pain everywhere) 2) ... the face (many differential ... children (pediatric SLE ... #diagnosis #sle
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm - Diabetes ... history Step #2 ... Hypernatremia #Management ... Algorithm #Sodium #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... - Differential ... Osmotic diuresis (see ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology