29 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... Renal #diseases #SLE ... #Systemic #Lupus ... Erythematosus #venn #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... (oral/iv) • Potassium-rich ... • Drugs • Diabetic ... Diagnosis #algorithm #nephrology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus ... #Nephritis #SLE ... diagnosis #management #nephrology
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies; SLE ... , systemic lupus ... Glomerulonephritis #Algorithm #Nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... Fluids Shift potassium ... Sodium bicarbonate Potassium ... function) - Loop diuretic ... #nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
mannitol) 3) Loop diuretic ... Metolazone) 5) Potassium-sparing ... #pharmacology #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE ... Diagnosis of Lupus ... Erythematosus #SLE ... #CNS #neurology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Chlorthalidone POTASSIUM-SPARING ... summary #table #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
• Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... treat non-renal SLE ... treat extra-renal SLE ... #Membranous #Lupus ... Treatment #management #nephrology