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diagnosis rheumatology hematology management erythematosus criteria syndrome activation algorithm apls arthritis chronic classification cll comparison cryofibrinogenemia disease druginduced eularacr hypercoagulable
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... , oral ulcers, Lupus ... • Immunologic Workup ... #lupus #Systemic
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Clinical and Immunologic ... Criteria CLINICAL ... nuclear antigen - Antiphospholipid
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Clinical Domains ... Immunologic domains: • Antiphospholipid ... Classification #Criteria #SLE ... #Systemic #Lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... • Immunologic Workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... fever syndromes Clinical ... Fever is the main clinical ... lupus erythematosus ... [SLE], AOSD) •
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... Cryofibrinogenemia Clinical ... and/or venous occlusions ... Diagnosis: • + Clinical ... HUS and HIT • Antiphospholipid
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... syndrome (GBS), systemic ... lupus erythematosus ... (SLE), polymyositis ... IU/I • SAMS clinical
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... ANA and RF (if clinical ... Arthritis #laboratory #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... ’s CLL Scoring system ... Leukemia #diagnosis #workup
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Hypercoagulable Workup ... - 1 or more clinical ... excluded Testing: • Lupus ... Hypercoagulable #Workup
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