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differential rheumatology management hematology signs algorithm msk oncology arthritis causes pathophysiology vasculitis workup disorders erythematosus infections infectiousdiseases primary systemic treatment
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... #differential #diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... permanent alopecia ... pain • Swan neck ... : • Symptoms limited
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... Disease: Discoid ... , Loose anagen syndrome ... DHEAS) • ANA ... #dermatology #Hairloss
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... (20%) Renal disease ... #diagnosis #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... • Loose anagen syndrome ... - Secondary to Skin ... Disease • ... #dermatology #Differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... ), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Associated with skin ... #Systemic #Lupus ... #Summary #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
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