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diagnosis rheumatology differential management systemic classification syndrome ana anca antibodies antibody antineutrophil antinuclear antinxp2 antinxp2dm clinical cryoglobulinemia cryoglobulins cutaneous dermatomyositis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Vesicopustule on erythematous ... Hypersensitivity vasculitis ... lesions • Discoid lupus ... erythematosus ... #dermatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Associated with skin ... severe disease Treatment ... #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... ANCA-associated vasculitis ... Seizures • Strokes Skin ... APLA/LAC: • Renal
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... #erythematosus #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... : erythematous nodules ... such as systemic lupus ... erythematosus, ... , and SLE) • Urinalysis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... in drug-induced SLE ... ANCA-Associated Vasculitis ... vasculitis - MPO
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... (e.g. systemic lupus ... erythematosus (
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... pulmonary and renal ... diseases, such as SLE ... : Erythematous nodules ... tract, and often causes
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment
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