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diagnosis differential causes rheumatology systemic hematology management ana antinuclear classification alopecia hairloss diffuse focal generalized joint nephrology patterns primary pruritus
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... SLE), Sjogren's ... Syndrome (SS), Polymyositis ... #Antinuclear #Antibodies
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
antineutrophil cytoplasmic antibodies ... antineutrophil cytoplasmic antibodies ... ; SLE, systemic ... lupus erythematosus ... Glomerulonephritis #Algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... APLA/LAC: • Renal ... 1, SCL-70, RNP antibodies ... : Drug induced SLE ... anticardiolipin antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus ( ... erythematosus ( ... Syndrome (SS), Polymyositis ... Arthritis, Sjögren Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Demyelinating Syndrome ... APS), Secondary ... #Erythematosus
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... block • Sjogren syndrome ... #Systemic #Lupus ... #Erythematosus
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Vesicopustule on erythematous ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus ... #dermatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus ... hemolysis • Renal ... Highly specific antibodies ... Classification #Criteria #SLE ... #Erythematosus
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Differential Diagnosis Algorithm ... Stevens-Johnson Syndrome ... • Systemic lupus ... erythematosus ... • Behcet's syndrome
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... erythematosus ... • Loose anagen syndrome ... erythematosus ... HairLoss #Alopecia #dermatology
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