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diagnosis rheumatology syndrome management skinrash ucsdh differential dress drugreaction eosinophilia erythematosus classification cutaneous oncology symptoms ana anca anesthesia anesthesiology antibodies
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Butterfly rash, Vasculitis ... #SLE #systemic ... erythematosus #signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... #lupus #Systemic
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... #table #rheumatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... medication (in this case ... #Dermatology #SkinRash ... Eosinophilia #Legs #Photo
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... medication (in this case ... #Dermatology #SkinRash ... Eosinophilia #Photo
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... which causes slowly ... a number of systemic ... Images #Clinical ... #Photo #Dermatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis ... vasculitis - MPO
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... lupus erythematosus ... purpura: strong sign ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... #Systemic #Lupus
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