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diagnosis rheumatology differential ana antibodies antinuclear vasculitis classification management symptoms activation alopecia antibody antineutrophil cryoglobulinemia cryoglobulins diseases hair hairloss hematology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... (SLE), Systemic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis ... cases • Sjögren syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease & renal ... block • Sjogren syndrome ... #Lupus #Erythematosus
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... diseases • In secondary ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs /
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... lupus erythematosus ... APLA/LAC: • Renal ... #Systemic #Lupus
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Demyelinating syndromes ... #SLE #systemic ... #erythematosus # ... signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... purpura: strong sign ... ) pattern: antibodies ... ) pattern: is usually ... vasculitis, and SLE
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Diagnosis #Management #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
erythematosus, ... , Loose anagen syndrome ... Examination: • Signs ... Vitamin D levels Systemic ... Differential #Diagnosis #dermatology
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