19 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Lupus Erythematosus ... #Lupus #Erythematosus ... #SLE #hematology ... #rheumatology #differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Reactive: - Systemic ... Inflammatory • Systemic ... Lupus Erythematosus ... Lymphocytes) - Monoclonal ... #Oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Cryoglobulinemia Renal-centered ... Significance #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus ... #SLE #systemic ... erythematosus #signs #symptoms
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Sjogren's ... (SLE), Systemic ... (SLE), Systemic ... rheumatology #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... Lupusreference #SLE ... #Systemic #Lupus ... autoantibodies #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... other symptoms
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... (total 50, renal ... Mnemonic #diagnosis #differential ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... APLA/LAC: • Renal ... : • Symptoms limited ... #Systemic #Lupus