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hematology differential rheumatology gammopathy disease erythematosus significance signs agglutinin algorithm anemia behcet causes chronic classification cll cold complications cutaneous diffuse
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... Diagnosis Neurologic-Centered ... #Gammopathy #Clinical ... #Differential #Diagnosis ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Lupus Erythematosus ... Lymphocytes) - Monoclonal ... Lymphadenopathy #LAD ... #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... constitutional symptoms ... hyperCalcemia, Renal ... #Significance #hematology ... #diagnosis #oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... #SLE #systemic ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Monoclonal IgM ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... APLA/LAC: • Renal ... : • Symptoms limited ... #Systemic #Lupus
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
treatment of infective symptoms ... ; vaccinations Renal ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... Oral aphthae : SLE ... • Arthritis: SLE ... refractory disease : monoclonal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lupus erythematosus ... Symptoms (Sx) in ... retinopathy Lab ... vasculitis, and SLE
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