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diagnosis rheumatology erythematosus differential systemic monoclonal eularacr gammopathy gap globulin mgrs oncology paraproteinemias protein proteingap significance slicc symptoms vasculitides vasculitis
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... - SEROSITIS - RENAL ... NEUROLOGIC - HEMOLYTIC ANEMIA ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... hemolysis • Renal ... #Criteria #SLE
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia ... erythematosus #signs
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Gammopathy of Renal ... does not meet criteria ... patients with MGUS ... Diagnostic Workup ... #Gammopathy #Renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... purpura: strong sign ... vasculitis, and SLE ... • Urinalysis (Renal ... #classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Gammopathy Include: • MGUS ... cancers, HCC, renal ... gastric tumors • Hematology ... differential #diagnosis #hematology
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