11 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: ... Sjögrens (15%) Skin ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Associated with skin ... #Systemic #Lupus ... #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... or 0.5 g/day → renal ... #rheumatology # ... nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Seizures • Strokes Skin ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
drug injections, renal ... malnutrition, HIV, SLE ... trauma, aplastic anemia ... steroid use Dx: skin ... #dermatology #skin
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... such as systemic lupus ... • ANA (Suggest CTD ... vasculitis, and SLE ... • Urinalysis (Renal
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
post-hypothermia • ↓ Renal ... Excretion: - Renal ... reabsorption) Workup ... 15 suggests ↓ renal ... Treatment #potassium #nephrology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
diagnosis: • Renal ... pruritus • Hematologic ... Iron deficiency anemia ... #Management #Nephrology ... #CKD
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gammopathy, and skin ... cancers, HCC, renal ... gastric tumors • Hematology ... differential #diagnosis #hematology