29 results
Renal involvement in Systemic Lupus Erythematosus (SLE)

Dr. Laurent ARNAUD @Lupusreference

#Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
Renal involvement ... in Systemic Lupus ... Lupusreference #Renal ... #SLE #Systemic ... #management #treatment
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... ) Blood (75%): Anemia ... Thrombocytopenia #Lupus ... #SLE #systemic
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... - SEROSITIS - RENAL ... NEUROLOGIC - HEMOLYTIC ANEMIA ... #Rheumatology #SLE
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... /systemic sclerosis ... severe disease Treatment ... #Lupus #Erythematosus
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic renal ... #Secondary #dermatology ... #Differential #
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... RA, SLE, PRV, Chronic ... Reticulocytosis • Renal ... #Differential # ... Algorithm #Causes #Hematology
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
delta/delta) to see ... Ketoacidosis, Renal ... loss of bicarb, Renal ... GI loss of H+, Renal ... Disorders #Evaluation #workup
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... (total 50, renal ... Mnemonic #diagnosis #differential ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... BUN: • Chronic renal ... failure/uremia ... #generalized #dermatology ... #Differential #
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... Impaired Clearance: Systemic ... liver Failure, Renal