13 results
diagnosis differential hematology oncology rheumatology symptoms algorithm leukemia manifestations neurology pathophysiology syndrome activation alopecia anca antibodies antibody antineutrophil chronic classification
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK • Bone ... Myopathy (Also caused ... #Complications ... pathophysiology #signs
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... other orthopedic complications ... XR, MRI to dx and ... • Hematogenous ... #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... #Antinuclear #Antibody
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... #SLE #Mucocutaneous ... pathophysiology #diagnosis #signs ... #symptoms #complications
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Auspitz sign, Koebner's ... soles • Discoid Lupus ... Erythematous - ... Papulosquamous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... erythematosus ... SJIA], systemic lupus ... erythematosus [ ... SLE], AOSD) • Infection
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... pain • Extra-CNS complications ... disorders (Systemic lupus ... erythematosus, ... neurology #symptoms #signs
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Disease: Discoid lupus ... erythematosus, ... erythematosus, ... Examination: • Signs ... Differential #Diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... kinase (BTK) Complications ... Warm AIHA • Bone ... leukemia • GI complications
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... such as systemic lupus ... erythematosus, ... purpura: strong sign ... SLE) • Urinalysis
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