14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... phenomenon (20%) Joints ... #SLE #systemic ... erythematosus #signs
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders ... arthritis - with the skin ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... thickening Signs ... Musculoskeletal: joint ... rheumatology #diagnosis #signs ... symptoms #testing #workup
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Malar rash • SLE ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... (SLE) Signs / ... Xeroderma (Dry skin
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Suggestive of: Lupus ... migrans: • Target sign ... Suggestive of systemic ... gabrieltalledop #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Arthritis: • Joint ... arthropathy • 90% joints ... #Systemic #Lupus
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... Episcleritis Signs ... and pain of the joints ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... vesicular eruption - Joints ... lupus erythematosus ... purpura: strong sign ... vasculitis, and SLE
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology