15 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... • Red plaques ... #Manifestations ... pathophysiology #diagnosis #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... Demyelinating Syndrome ... #SLE #CNS #neurology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Disease: Discoid lupus ... , Loose anagen syndrome ... Examination: • Signs ... Vitamin D levels Systemic ... Differential #Diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... permanent alopecia ... • Nonscarring alopecia ... #Systemic #Lupus
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... autoimmune disorders (Systemic ... lupus erythematosus ... #diagnosis #neurology ... #symptoms #signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... main clinical manifestation ... • Hemorrhagic manifestations ... lupus erythematosus ... [SLE], AOSD) •
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... systemic disease ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
& Mu) Skin Manifestations ... et diutinum Neurologic ... Manifestations: ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Red flags (PHANTOMS ... papilledema • Horner syndrome ... pupil (AACG) • Systemic ... symptoms and signs ... #neurology #PHANTOMS
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Musculoskeletal system ... Episcleritis Signs ... - Lupus - Leukemia ... #diagnosis #dermatology