24 results
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... Signs/Symptoms ... Alopecia, Fever, ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... #SLE #systemic ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
, Loose anagen syndrome ... Examination: • Signs ... DHEAS) • ANA ... Vitamin D levels Systemic ... Differential #Diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... permanent alopecia ... : • Symptoms limited ... #Systemic #Lupus
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... • Red plaques ... pathophysiology #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... #Systemic #Lupus ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Workup: - ANA ... months to years) Systemic ... Photosensitivity, Alopecia ... #table #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... #Symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... (SLE), should have ... other symptoms