18 results
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... 60-80% Association ... overlap syndromes ... Negative association ... autoantibodies #Systemic
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... #Rheumatology #Associations
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have ... Joint #Disorders #msk
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... (SLE): ANA (anti-nuclear ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... Rheumatology #diagnosis #associations
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
may be seen in association ... (PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... (SLE) Signs /
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... Skin Disease Classification ... Neuropsychiatric systemic ... #Systemic #Lupus
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... • Cyanosis Red ... • Nephrotic syndrome ... #Secondary #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Diagnosis #Management #Hematology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
bite, Migratory red ... Arthritis • Systemic ... Lupus Erythematosus ... Sicca) Syndrome ... Inflammatory #JointPain #MSK
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... lupus erythematosus ... (SLE), rheumatoid ... diagnosis #types #classification