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diagnosis rheumatology ana antibodies pathophysiology summary table activation anca antineutrophil arthritis classification comparison criteria differential disease diseases druginduced hematology hypersensitivity
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Antibody (ANA) ... #IMDAMNSHARP #sle ... #systemic #lupus ... #erythematosus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Lupus Erythematosus ... #Rheumatology #SLE ... #Lupus #Erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... (SLE), Systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... /systemic sclerosis ... #Lupus #Erythematosus ... #rheumatology #management
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Small antigen-antibody ... the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... versus DIL • Laboratory ... #lupus #Systemic ... #Erythematosus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and fever) and laboratory ... Female • Peaks 3rd ... lupus erythematosus ... #Systemic #Lupus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... - IgG or IgM antibody ... - Red blood cell ... arthritis, and systemic ... lupus erythematosus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... months to years) Systemic ... Lupus Erythematosus ... versus DIL • Laboratory ... Usual therapeutic management
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