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diagnosis rheumatology differential classification algorithm acute ana anca antibody antineutrophil antinuclear comparison criteria diseases druginduced eularacr high hyperkalemia kidneyinjury naildisorders
Renal involvement in Systemic Lupus Erythematosus (SLE) Dr. Laurent ARNAUD @Lupusreference #Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
Renal involvement ... in Systemic Lupus ... #lupus #nephritis ... #SLE #Systemic ... SLE #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... lupus erythematosus ... APLA/LAC: • Renal ... #Systemic #Lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... hemolysis • Renal ... Highly specific antibodies ... Classification #Criteria #SLE ... #Systemic #Lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... nephritis, NPSLE ... Positive in 60-80% of cases ... #lupus #Systemic ... #Erythematosus
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... at least 50% Renal ... Drugs • Emboli Systemic ... Glomerulonephritis • Anti-GBM antibodies ... Acute Interstitial Nephritis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... Lupus Erythematosus ... nephritis, NPSLE ... Usual therapeutic management ... rheumatology #diagnosis #management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Chronic renal ... discoloration) • Nephrotic ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... tract, and often causes ... lupus erythematosus ... C-ANCA) pattern: antibodies ... vasculitis, and SLE
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... cirrhosis: 3%-20% Renal ... • Interstitial nephritis ... Distal (Type I) renal ... Rheumatology #Diagnosis #Management
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