16 results
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... the cause: • Arthritis ... #Immunology #pathophysiology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... Suggestive of systemic ... gabrieltalledop #dermatology ... #arthritis #skin ... #differential #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... #SLE #systemic
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... - with the skin ... Lupus - with Systemic ... (SLE), should have ... like “butterfly rash
SOAP BRAIN MD Mnemonic for Systemic Lupus Erythematosus (SLE)

S - Serositis (Pleuritis, Pericarditis)
O - Oral Ulcers
A
MD Mnemonic for Systemic ... Lupus Erythematosus ... Oral Ulcers A - Arthritis ... A - ANA I - Immunologic ... #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... NPSLE rare, Malar rash ... months to years) Systemic ... Manifestations: Malar rash ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Female • Peaks 3rd ... Decade Skin ... Differential Diagnosis ... #Systemic #Lupus
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus ... #dermatology #oncology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Scaring alopecia • Red ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs