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Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
thalassemia, and some hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
associated with hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
This smear was from ... spherocytosis and hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
to be seen in hemolytic ... microangiopathic hemolytic ... intravascular coagulation, hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
peripheral blood smears ... can be found in hemolytic ... #Clinical #Path ... BloodSmear #Blood #Smear
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing in Hemolytic ... Extravascular Hemolysis ... LDH Peripheral smear ... Carboxyhemoglobin #Hemolytic ... diagnosis #hematology #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... of anemia and hemolysis ... Abnormal peripheral smear ... Immune-mediated Hemolysis ... • Autoimmune Hemolytic
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... C3d • Blood smear ... Antibody #Autoimmune #Hemolytic
Hemolytic Anemia - Hemolysis Diagnostic Workup

Infographic by: Howard Ong

#Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... - Hemolysis Diagnostic ... Howard Ong #Hemolysis ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Peripheral blood smear ... Immune mediated hemolysis ... Microangiopathic hemolytic ... UnremarkableLab #Hemolytic