10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... - pulmonary opacities ... • Steroids: IV ... unless severe APLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... - ACS, AKI, ... organ damage • Treatment ... #TLS #diagnosis
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... CBC, vitamin D level ... ventilated • CXR ... #Exacerbation #treatment ... #pulmonary
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Insufficiency, Liver ... • Obstructive: Pulmonary ... Abdominal compartment syndrome ... #criticalcare #algorithm
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... Blood cultures • CXR ... early disease) • CXR ... decubitus - air fluid level ... Lung #Abscess #pulmonary
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... • Diagnosis of ... Torsemide) • Acute pulmonary ... Association class IV ... Tolvaptan) • Treatment
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... feed them or give IV ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Disease: • 10%-15% Pulmonary ... risk PE, Pulmonary ... vasculitis: 10%-16% Liver ... Adenocarcinoma Treatment
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential Diagnosis ... night sweats, fever ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... hematuria, + RF Treatment
Abdominal Compartment Syndrome & Intrabdominal Pressure Measurement
APP (Abdominal Perfusion Pressure) = MAP (Mean Arterial Pressure) -
Abdominal Compartment Syndrome ... after previous treatment ... transducer at the level ... syringe to fill with IV ... #Instructions #diagnosis