494 results
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... Trimethroprim/Sulfamethoxazole ... Kat_Watson #Drug #Induced
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... associated with drug-induced ... Chlorthalidone, Sulfamethoxazole
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
, trimethoprim-sulfamethoxazole ... Medications #Dysgeusia #Induced
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Thiazide induced ... Pathophysiology • Reduced ... mechanism • Reduced ... #Thiazide #induced
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Beta-lactams, vancomycin, sulfamethoxazole-trimethoprim ... ciprofloxacin, sulfamethoxazole
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
of trimethoprim–sulfamethoxazole ... #trimethoprim #sulfamethoxazole
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
- Trimethoprim/Sulfamethoxazole
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
stiffness #Drug-induced ... Corticosteroid-induced ... myopathy #Statin-induced ... myopathy #Cocaine-induced
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
• Trimethoprim-sulfamethoxazole
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Trimethoprim / Sulfamethoxazole