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diagnosis oncology causes management algorithm hemolysis leukemia workup chronic classification cll hemolytic intravascular rheumatology agglutinin analysis approach arterial atlas bandemia
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
- Differential ... compression and DVT ... APLS:PLT ↓ HEMATOLOGIC ... #Differential # ... Diagnosis #clots #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... cells: Sickle cell disease ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Normochromic RBCs on Smear ... Disease • Marrow ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... hemolytic-uremic syndrome (ST-HUS ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Normal Blood Smear ... • Pancreatic Disease ... • Liver Disease ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... , Liver diseases ... uremic syndrome, Thrombotic ... key #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... cells can indicate disease ... • Neutropenia, anemia ... workup #oncology #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... #Diagnosis #hematology
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