16 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic Microangiopathies ... - Primary Thrombotic ... TableThrombotic ... MatthewHoMD #Thrombotic ... Microangiopathies #Primary #Thrombotic
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... testing for TTP #Thrombotic ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... vasculopathy, thrombosis ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
PE) or arterial thrombosis ... thrombosis or high ... Duration: ⊕Thrombosis ... months ⊖Thrombosis ... consider a/c 2-3m (↑ thrombosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dependent edema, and thrombosis ... artery or vein thrombosis ... • Mesenteric thrombosis ... • Pelvic vein thrombosis ... active flare • Thrombosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... - bleeding or thrombosis ... antibodies/SRA - + Thrombosis ... presence of large thrombosis ... #Coagulation #diagnosis
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
antibodies (aPL): • Lupus ... at least: • 1 clinical ... or small-vessel thrombosis ... presence of 1 clinical ... to be present Treatment
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... to cold IgG • Lupus ... Hyperviscosity (Thrombosis ... beds-renal, retinal, DVT ... #Differential #Diagnosis
Greater Saphenous Vein Thrombosis on POCUS
Pt-leg pain/redness/swelling. Proximal TRV image. 
Diagnosis: Greater Saphenous Vein Thrombosis without
Saphenous Vein Thrombosis ... Diagnosis: Greater ... Saphenous Vein Thrombosis ... Saphenous #Vein #Thrombosis ... #POCUS #clinical