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Syphilis Staging - Primary, Secondary, Latent and Tertiary - Timing and Features

Primary syphilis classically presents with
- Primary, Secondary ... Secondary syphilis ... infection and late ... infection. ... #Diagnosis #Syphilis
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
Primary - 2-6 weeks ... after infection ... • Asymptomatic Secondary ... 2 months after primary ... #progression #diagnosis
Causes of Encephalopathy - Differential Diagnosis Algorithm
Hyperacute:
 - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
- Differential Diagnosis ... Hyperacute: - Primary ... Neurologic: Vascular ... (syphilis, HIV-associated ... #Differential #Diagnosis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Primary Syphilis ... Secondary Syphilis ... and secondary syphilis ... or secondary syphilis ... #Primary #Secondary
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
- Differential Diagnosis ... Tenosynovitis) • Secondary ... Syphilis (Red/Copper ... like rash) • Primary ... #Differential #Diagnosis
Primary Syphilis
Usually, a single ulcer (chancre) appears at the site where the bacteria entered the body.
Primary Syphilis ... administered, the infection ... #Primary #Syphilis ... #Chancres #Diagnosis ... #Clinical #Photo
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... Disease process primarily ... nephropathy • Secondary ... Post-infectious ... #nephrology
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... Early Primary: ... lymphadenopathy Early Secondary ... first year of infection ... symptoms #signs #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis ... treatment, the infection ... #Secondary #Syphilis ... #Rash #Diagnosis ... #Clinical #Photo
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
- Differential Diagnosis ... acuminata) • Secondary ... Syphilis (condyloma ... - Painless • Primary ... syphilis (chancre