15 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... Antigen-antibody complex ... T cells. ... T-cells recruit ... allergy #table #classification
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
it is entirely T-Cell ... exposure to allergen causes ... allergen-specific T-Cell ... exposure, because T-Cell ... activate macrophages
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T ... Antigen-antibody complexes ... cytokines, which activate ... Hypersensitivity #Types #Classification ... #Pathophysiology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... germinative skin cells ... Causes: 1) Exfoliative ... 4) Skin-homing T-cells
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Differential Diagnosis Algorithm ... fungoides (cutaneous T-cell ... Viral - Herpes simplex ... Differential #Diagnosis #Algorithm ... #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... as common - T ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
surfaces causes ... it is entirely T-Cell ... exposure to allergen causes ... allergen-specific T-Cell ... exposure, because T-Cell
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... Red blood cells ... • Immune-complex ... #Causes
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... hair follicles -> causes ... inflammation (complex ... decr release and activity ... Manifestations #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... node and AV node activity ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology