931 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication Targets ... the different pathophysiologic ... #Diabetes #Pathophysiology ... #Medication #Targets
Classification of COVID-19 Disease States and Potential Therapeutic Targets

Viral Response Phase -> Host Inflammatory Response Phase
Stage
Potential Therapeutic Targets ... Classification #Diagnosis #Pathophysiology ... #Therapeutic #Targets
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... • Dosing and Targets
Immune Checkpoint Inhibitors

PD-1 inhibitors
 - Nivolumab
 - Pembrolizumab
CTLA-4 inhibitors
 - Ipilimumab
 - Tremelimumab
PD-L1 inhibitors
 - Atezolizumab
Checkpoint #Inhibitors #Targets ... #Pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH and SAH BP target ... Target MAP: 80. ... Target CPP 60. ... Pressure #ICP #Pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Neuronal cell surface targeted ... RheumaticFever #pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
understanding of pathophysiology ... To propose new targeted
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
weight (kg) x (target ... #pharmacology #pathophysiology
Drugs with Actions on Bronchial Smooth Muscle
Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
#SmoothMuscle #Pathophysiology ... Pharmacology #Pulmonary #Targets
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
autoantibodies can target ... Rheumatic #Fever #Pathophysiology