7 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... Anaphylaxis, Acute Renal ... severe APLS, organ dysfuxtion
Evaluation and Management of Hyperkalemia

As with hypokalemia, the immediate danger of hyperkalemia is its effect on
The absence of symptoms ... with underlying renal ... dysfunction merit ... Hyperkalemia #Evaluation #Algorithm
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... • Depressive symptoms ... is similar to PML ... etiologies and PML ... Behavioral • Motor dysfunction
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... Life-threatening organ dysfunction ... • Pathophysiology ... • Symptoms: Fever ... pulses • The Renal
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... , and possibly renal ... Features: • Many symptoms ... patients have no symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Neurological symptoms
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Pathologic fractures Renal ... resorption, Incr renal ... causes middle ear dysfunction ... PagetsDisease #pathophysiology ... diagnosis #signs #symptoms