9 results
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #differential #causes ... #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... COMMON CAUSES + ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death -> end-organ dysfunction ... #Classification ... #diagnosis #management ... #differential #causes ... #classification
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... (16%) • Shock ... Treat primary cause ... #treatment #management ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver dysfunction ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... #pathophysiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... #Causes #Hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... the underlying cause ... Syndrome #diagnosis #management
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis - Management ... Algorithm Assess ... exclude other causes ... Multiorgan failure or shock ... #Algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Pathophysiology ... #Hematology #HemeOnc