12 results
diagnosis liver algorithm transaminitis hepatitis syndrome aflp apml blood chemistry differentiation dili drug fatty function gastroenterology hepatocellular idiosyncratic induced interpretation
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
(LFTs) - Differential ... Hepatopathy • Acute ... Drug-induced liver injury ... #LFTs #Differential ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... → liver test abnormalities ... #Differential # ... Diagnosis #hepatology ... Transaminitis #LFTs
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... thrombocytopenia + MAHA ±AKI ... Direct antiglobulin test ... #Diagnosis #Management ... #Algorithm #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Mixed - Check Acute ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... extrahepatic source - Tests ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... fever - ACS, AKI ... , acute limb ischemia ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
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