24 results
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Origin (FUO) - ... Further Workup ... Test for the respective ... values supporting hematologic ... #workup #diagnosis
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Unknown Origin (FUO ... - Differential Diagnosis ... Lemierre's syndrome ... Malignancy: - Hematologic ... #Differential #Diagnosis
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
the preferred test ... typically part of the workup ... • Test all patients ... : • Fever, chills ... #Microbiology #InfectiousDiseases
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Irritable Bowel Syndrome ... and Workup Summary ... cultures, but test ... missing things" → fewer ... #Diagnosis #workup
Possible Algorithm for Workup of Fever of Unknown Origin (FUO)
Tier 1 Workup:
 • CBC, comprehensive metabolic
of Fever of Unknown ... Origin (FUO) Tier ... • Additional tests ... DrEricStrong #FUO ... #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... - Nonremitting fever ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... death Neutropenic Fever ... • Dyspnea at rest ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Subacute-Acute: • Common: fever ... Differentiation #Syndrome ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... • Richter’s Syndrome ... #workup #oncology ... #hematology