12 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... PD deficiency, Pulmonary ... uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... result in severe anemia ... indirect antiglobulin tests ... anemia Indirect ... #Workup #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency Anemia ... extravascular) hemolysis ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... Algorithm #ferritin #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Test: Donath-Landsteiner ... test #cold # ... #anemia #hematology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
the preferred test ... typically part of the workup ... • Test all patients ... Distal joints, knees ... #Microbiology #InfectiousDiseases
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... • Neutropenia, anemia ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... Hematologic malignancy ... Bone Marrow - Anemia ... discomfort, • +/- Hemoptysis ... #infectiousdiseases