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diagnosis management cancer differential emergencies oncologic aki chronic classification cll dermatology differentiation gravis hemeonc injury kidney leukemia lymphocytic lysis mds
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Differentiation #Syndrome ... #management #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
malignancies Treatment ... sinusoidal obstructive syndrome ... Capillary leak syndrome ... • Tumor lysis syndrome ... #AKI #Cancer #Oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... of breath • Neurologic ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... Walid Malki, MD, MS ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... formed or don’t work ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... leukemia • Sezary syndrome ... #oncology #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome ... aspiration and acute
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Acute febrile ... dermatosis (Sweets Syndrome ... classical Sweet syndrome ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
TLS (tumor-lysis syndrome ... decompression SVC syndrome ... Hyperviscosity syndrome ... Cytokine-release syndrome ... Differentiation syndrome
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