53 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... diagnosis and treatment ... • Cogan syndrome ... • Systemic lupus ... #neurology #inflammatory
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... & renal involvement ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: •
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Syndrome Definition ... Syndromes: • ... Infection, Alport Syndrome ... , biopsy By Tess ... #Syndrome #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
parenchymal disease ... disease - Renal ... • Cushing’s syndrome ... Mineralocorticoid excess syndromes ... Causes #Screening #Workup
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Liver function tests ... Macrophage #Activation #Syndrome
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... Rhabdomyolysis, Tumor lysis syndrome ... acidosis, DKA Kidney Disease ... CKD Increased Renal ... #phosphate #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... in Behcet syndrome ... adenopathy (PFAPA) syndrome ... hyperimmunoglobulin D syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... cases • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology